Nitrimidazine (Naxogin) compared with metronidazole (Flagyl) in the treatment of trichomonal vaginitis.

For more than 10 years very satisfactory results have been obtained in the treatment of trichomonal vaginitis using the standard 7-day course of metronidazole 200 mg. three times a day (Rodin, King, Nicol, and Barrow, 1960). In a recent trial it was shown that a 5-day course of 400 mg. twice daily produced equally satisfactory results, and was probably an easier regime from the patient's point of view (McClean, 1971). Nitrimidazine (Naxogin) is a related compound introduced in Italy for treatment of the same condition, and equally satisfactory or better results are claimed for it when used at a dosage of 250 mg. twice daily for 6 days (Emanueli and de Carneri, 1969; Signorelli and Emanueli, 1969). In the trial to be described the two compounds